Tumor cells can hijack the checkpoint pathways to avoid attacks from the immune system, thus studying the immune checkpoint protein can provide important insights in cancer development and therapies. Immune checkpoint pathways involve both costimulatory and inhibitory proteins. The costimulatory receptors transduce signals to promote immunity against pathogens. The inhibitory receptors negatively regulate cell activation to prevent excessive inflammation. Bowen Bioscience provides a collection of human immune checkpoint proteins to assist in the research and development of checkpoint proteins. For information of more proteins, please check the company directly.
In recent years, immune checkpoint agonist or antagonist antibodies have raised great attention in combating cancer and several check point antibodies have gain FDA or CFDA approval as monotherapy or combination cancer therapies. Encouraged by the success, researchers have expanded their investigations into other checkpoint proteins in order to find better ways to treat cancer. Bowen Bioscience is focused in making monoclonal antibodies from mouse, rabbit, and camel; optimize and humanize against oncogenes for co-development and licensing opportunities. Please contact the company to inquire about the specific targets of the antibodies being developed or in the pipeline.

Endotoxin Assay Kits

Endotoxin test is the most critical quality control test required by the FDA for all drugs in their final stages of formulation. Endotoxins are invariably associated with every gram-negative bacteria, so they cause severe reactions in humans and animals and retain high toxic activity even present at low concentration. In addition, endotoxins are suspected to play an important role in the occurrence and development of many different diseases. Bowen strongly recommends innovative detection technique to detect endotoxin. Bowen's Endotoxin Assay Kits can be well used in in vitro end-product endotoxin test for human and animal parenteral drugs, biological products, and medical devices.

Key Features

  • Good linearity and good reproducibility
  • Ready-to-use reagents and materials, such as tips, endotoxin-free tubes,etc.
  • High sensitivity and broad application range
  • Competitive price
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